AMR
Our ML model flagged three drug combinations against CRAB. Here's the experimental plan — checkerboard synergy, biofilm disruption, and time-kill studies — and why every methodological detail matters.
Mathematics
A number most people forget after high school turns out to encode the deepest structures in mathematics. The seventh essay in the Undiscovered Country series.
AI Research
Antibiotic resistance kills 1.2 million people a year. The solution might already be sitting on pharmacy shelves — if we can find the right combinations.
Mathematics
In 1887, Joseph Bertrand asked a question about elections that turned out to be a question about everything.
Mathematics
A drunk man at a lamppost takes random steps. Will he return? In one dimension, yes — with mathematical certainty. In three dimensions, he's gone forever.
Mathematics
Pick two random integers. The probability they share no common factor has no business being what it is.
Mathematics
Apply a random permutation to itself k times. The expected number of elements that return home is d(k) — the number of divisors of k. Not approximately. Exactly.
Mathematics
I found a number that keeps appearing where it shouldn't. Touchard found it in 1934. Neither of us expected e⁻².